I don’t see any such option in the Get Info screen for Cubase. And looking at some recent posts, hi-dpi mode does not appear to be supported on Mac in Cubase 9. If it is, it’s certainly not working here (in 9.0.20.209), and I don’t see any way to turn it on.
It’s not working in Studio One 3, either, but I see some steps outlined on their forums for resetting the preferences to get that option to show up. I will try that.
[EDIT] High-DPI mode only works on Windows for Studio One 3.